Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868716 | 1.00 | GSR (0.45) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL12833333 | 0.94 | GSR (0.53) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL21103612 | 0.94 | GSR (0.53) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL18868852 | 0.94 | GSR (0.53) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL24449947 | 0.92 | GSR (0.52) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL20388742 | 0.88 | GABRR1 (0.46) | GSRDPP7DPP8DPP9GABRR1 | |
| SCHEMBL18819968 | 0.88 | GABRR1 (0.46) | GSRDPP7DPP8DPP9GABRR1 | |
| SCHEMBL25858686 | 0.85 | DPP7 (0.50) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL12278737 | 0.81 | GSR (0.50) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL17173859 | 0.81 | GSR (0.50) | GSRDPP7DPP8DPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728218-B1 | AMINO INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-01 | — | — | EP | disclosed |