Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Flucytosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161858 | 0.73 | — | — | |
| SCHEMBL30510082 | 0.73 | — | — | |
| SCHEMBL24549964 | 0.70 | CHEK1 (0.34) | — | |
| SCHEMBL29551741 | 0.70 | ABL1 (0.32) | — | |
| SCHEMBL2512345 | 0.68 | GRIA1 (0.36) | — | |
| SCHEMBL30092 | 0.68 | GRIA1 (0.36) | — | |
| SCHEMBL11542411 | 0.68 | — | — | |
| SCHEMBL29711241 | 0.66 | MAPT (0.38) | — | |
| SCHEMBL4433604 | 0.65 | POLB (0.42) | — | |
| SCHEMBL18081882 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27490 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144879-A1 | ANTI-VIRAL AND HEPATIC-TARGETED DRUGS | AI-BIOPHARMA (FR) | 2026-05-28 | — | — | US | claimed |
| WO-2026107113-A1 | MODIFIED CELLS FOR PROGRAMMING EXTRA ENVELOPED VIRUSES (EEVs) AND THEIR USE FOR PRODUCING THE EEVs, THE PROGRAMMED EEVs AND USES THEREOF | CALIDI BIOTHERAPEUTICS (NEVADA), INC. (US) | 2026-05-21 | — | — | WO | claimed |
| US-20260124224-A1 | USE OF COMBINED COMPOSITION IN PREPARING DRUG FOR RESISTING FUNGAL AND BACTERIAL INFECTIONS | NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY (CN) | 2026-05-07 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| US-12618050-B2 | Engineered polypeptides that exhibit increased catalytic efficiency for unnatural cofactors and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-05 | — | — | US | claimed |
| EP-4719384-A2 | COMPOUNDS WITH ANTIFUNGAL PROPERTIES | Trustees of Dartmouth College (US) | 2026-04-08 | — | — | EP | claimed |
| US-12582696-B2 | Debaryomyces species as an indicator of non-healing ulcers in Crohn's disease | WASHINGTON UNIVERSITY (US) | 2026-03-24 | — | — | US | claimed |
| EP-4709870-A1 | REVISION OF GENETIC MATERIAL USING DIRECT REPLACEMENT EDITING | Transit Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4704904-A1 | TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD | Tambo, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4705508-A1 | METHODS FOR ANALYSIS OF DNA METHYLATION | Guardant Health, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| CN-1071577-A | Handle the toxicity of chemotherapy reagent and Anti-virus agent with acylated pyrimidine nucleosides | PRO NEURON INC (US) | 1993-05-05 | — | — | CN | claimed |
| CN-1067654-A | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1993-01-06 | — | — | CN | claimed |
| CN-1065065-A | Preparation method of 2-hydroxymethyl-5- (5-fluorocytosin-1-yl) -1, 3-oxathiolane | UNIV EMORY (US) | 1992-10-07 | — | — | CN | claimed |
| EP-0126684-B1 | DRUG DELIVERY SYSTEM UTILIZING THERMOSETTING GELS | MERCK & CO. INC. (US) | 1991-08-28 | — | — | EP | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
| EP-0094329-B1 | TANNING PROCESS FOR RENDERING LEATHERS MYCOSTATIC, ANTIMYCOSIC AND ANTIFUNGICIDAL, AND ARTICLES PRODUCED THEREBY | Roux, Joel (FR) | 1986-01-22 | — | — | EP | claimed |
| EP-0126684-A2 | Drug delivery system utilizing thermosetting gels | MERCK & CO. INC. (US) | 1984-11-28 | — | — | EP | claimed |
| US-4484925-A | USING BIOCIDAL AGENTS ON METAL COMPLEXES | ROUX JOEL (FR) | 1984-11-27 | — | — | US | claimed |
| US-4474751-A | SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER | MERCK & CO., INC. (US) | 1984-10-02 | — | — | US | claimed |
| US-4144327-A | SYNERGISTIC | G. D. SEARLE & CO. (US) | 1979-03-13 | — | — | US | claimed |