Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 8/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 5/20 | 0.43 |
| ▸ | PAK4 | O96013 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | PAK3 | O75914 | 2/20 | 0.41 |
| ▸ | PAK2 | Q13177 | 2/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065120 | 0.90 | IGF1R (0.40) | IGF1RPAK1PAK4AURKASRC | |
| SCHEMBL24065151 | 0.88 | SRC (0.50) | IGF1RPAK1PAK4AURKASRC | |
| SCHEMBL24065254 | 0.85 | NEK1 (0.45) | IGF1RPAK1PAK4AURKASRC | |
| SCHEMBL29593314 | 0.84 | JAK1 (0.38) | IGF1RAURKA | |
| SCHEMBL24065231 | 0.84 | PAK1 (0.48) | IGF1RPAK1PAK4SRCPAK3 | |
| SCHEMBL24065099 | 0.84 | PAK4 (0.60) | IGF1RPAK1PAK4SRCNEK1 | |
| SCHEMBL24065028 | 0.84 | PAK4 (0.60) | IGF1RPAK1PAK4SRCNEK1 | |
| SCHEMBL24065077 | 0.83 | NEK1 (0.48) | IGF1RPAK1PAK4AURKASRC | |
| SCHEMBL29592850 | 0.83 | NEK1 (0.48) | IGF1RPAK1PAK4AURKASRC | |
| SCHEMBL25241183 | 0.83 | IGF1R (0.43) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369710-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369710-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | MYC, MYCBP, MYCBP2 | IGF1R 1878/4885PAK1 222/4885PAK4 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.