SCHEMBL24065809

SCHEMBL24065809

CCCCN(CCNC)CCNC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
PRMT3 O60678 1/20 0.43
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT1 Q99873 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
KDM5A P29375 4/20 0.37
PHF8 Q9UPP1 2/20 0.35
KDM4C Q9H3R0 2/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA9 Q16790 2/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL681618 1.00 EPHX1 (0.48) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL20118741 0.95 EPHX1 (0.44) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL19575770 0.90 EPHX1 (0.44) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL12478475 0.90 EPHX1 (0.44) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL681370 0.90 EPHX1 (0.55) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL27427924 0.89 EPHX1 (0.39) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL20283561 0.89 EPHX1 (0.39) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL23223465 0.89 EPHX1 (0.39) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL12559633 0.89 EPHX1 (0.39) EPHX1PRMT3CARM1PRMT6PRMT1
SCHEMBL18732127 0.88 EPHX1 (0.48) EPHX1PRMT3CARM1PRMT6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037641-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-07-16 US disclosed
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-06-22 US disclosed
US-20210369867-A1 LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY NUTCRACKER THERAPEUTICS, INC. (US) 2021-12-02 US disclosed
US-9957291-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2018-05-01 US disclosed
US-20170321268-A1 MODIFIED NUCLEOTIDE REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2017-11-09 US disclosed
US-20170145495-A1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2017-05-25 US disclosed
US-20170145502-A1 MODIFIED NUCLEOTIDE REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2017-05-25 US disclosed
US-20160237279-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-18 US disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170321268-A1 MODIFIED NUCLEOTIDE REAGENTS POLL, POLN, POLM EPHX1 4179/4885PRMT3 3919/4885CARM1 4673/4885
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 EPHX1 1999/4885PRMT3 3851/4885CARM1 2894/4885
US-12037641-B2 Modified nucleotide reagents POLL, POLN, POLM EPHX1 4179/4885PRMT3 3919/4885CARM1 4673/4885
US-20170145495-A1 PROTECTED DYE-LABELED REAGENTS POLL, POLB, POLM EPHX1 3740/4885PRMT3 4186/4885CARM1 4690/4885
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 EPHX1 1999/4885PRMT3 3851/4885CARM1 2894/4885
US-20210369867-A1 LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY PHOSPHO1, PLIN3, CETP EPHX1 4154/4885PRMT3 432/4885CARM1 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.