Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472510 | 0.86 | HDAC11 (0.55) | HDAC6HSD11B1HDAC11HDAC4HDAC7 | |
| SCHEMBL20535895 | 0.74 | HDAC6 (1.00) | HDAC6HDAC11HDAC4HDAC7HDAC8 | |
| SCHEMBL2406722 | 0.74 | CYP17A1 (0.50) | HDAC6 | |
| SCHEMBL461685 | 0.73 | ESR1 (0.61) | HDAC6HSD11B1MEN1KMT2AKDM4E | |
| SCHEMBL2475381 | 0.70 | HDAC6 (0.52) | HDAC6HDAC8MEN1KMT2AEPHX2 | |
| SCHEMBL2413536 | 0.70 | HDAC6 (0.56) | HDAC6HDAC8MEN1KMT2AEPHX2 | |
| SCHEMBL2409200 | 0.69 | HDAC6 (0.58) | HDAC6HDAC11HDAC4HDAC7HDAC8 | |
| SCHEMBL29151632 | 0.68 | HDAC6 (0.54) | HDAC6HDAC8 | |
| Dopamantine SCHEMBL122326 | 0.68 | SPHK2 (0.67) | HSD11B1MEN1KMT2AKDM4EHTT | |
| SCHEMBL11740707 | 0.67 | SMN1; SMN2 (0.73) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |