⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426193 | 0.93 | CA14 (0.33) | — | |
| SCHEMBL31618231 | 0.88 | CA14 (0.37) | — | |
| SCHEMBL19437468 | 0.88 | CA14 (0.37) | — | |
| SCHEMBL25755543 | 0.88 | CA14 (0.32) | — | |
| SCHEMBL15268983 | 0.87 | — | — | |
| SCHEMBL24068405 | 0.84 | CA14 (0.36) | — | |
| SCHEMBL23766011 | 0.83 | CA14 (0.33) | — | |
| SCHEMBL24068831 | 0.82 | BLM (0.37) | — | |
| SCHEMBL23766081 | 0.82 | BLM (0.37) | — | |
| SCHEMBL25755471 | 0.82 | CA14 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369853-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-12-02 | — | — | US | disclosed |