Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Mercaptoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptoethanol SCHEMBL9436556 | 0.91 | — | — | |
| Butane SCHEMBL8423202 | 0.87 | — | — | |
| Propanol SCHEMBL18191727 | 0.87 | — | — | |
| 2-Mercaptoethanol SCHEMBL5912606 | 0.86 | — | — | |
| 2-Mercaptoethanol SCHEMBL16756659 | 0.86 | — | — | |
| Alcohol SCHEMBL890729 | 0.86 | — | — | |
| 2-Mercaptoethanol SCHEMBL5702 | 0.85 | — | — | |
| 2-Mercaptoethanol SCHEMBL3727625 | 0.85 | — | — | |
| 2-Mercaptoethanol SCHEMBL26658188 | 0.84 | — | — | |
| 2-Mercaptoethanol SCHEMBL8849693 | 0.82 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987775-A | Proportioning detection method of multi-RNA mixture and application thereof | 珠海丽凡达生物技术有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-112662732-A | High-throughput rapid screening method of pantothenate synthetase mutants | 浙江工业大学 | 2021-04-16 | — | — | CN | claimed |
| CN-106106473-A | A kind of compositions preventing and treating Caulis et Folium Brassicae capitatae diamondback moth and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | claimed |
| EP-0185066-A1 | — | UNIV PASTEUR | 1986-06-25 | — | — | EP | claimed |
| WO-1986000304-A1 | SULPHUR-CONTAINING DERIVATIVES OF PARA-METHOXYCINNAMIC ACID, PRODUCTION PROCESSES THEREOF, DERMO-PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM AND APPLICATIONS | UNIVERSITE LOUIS PASTEUR (STRASBOURG I) (FR) | 1986-01-16 | — | — | WO | claimed |
| CN-109593068-B | Intermediate of ROR gamma inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| US-11325887-B2 | Methods for forming peroxyformic acid and uses thereof | ECOLAB USA INC. (US) | 2022-05-10 | — | — | US | disclosed |
| CN-112662732-A | High-throughput rapid screening method of pantothenate synthetase mutants | 浙江工业大学 | 2021-04-16 | — | — | CN | disclosed |
| US-10899707-B2 | Methods for forming peroxyformic acid and uses thereof | ECOLAB USA INC. (US) | 2021-01-26 | — | — | US | disclosed |
| US-20200157046-A1 | METHODS FOR FORMING PEROXYFORMIC ACID AND USES THEREOF | ECOLAB USA INC. | 2020-05-21 | — | — | US | disclosed |
| US-20190152906-A1 | METHODS FOR FORMING PEROXYFORMIC ACID AND USES THEREOF | ECOLAB USA INC. | 2019-05-23 | — | — | US | disclosed |
| CN-106106473-A | A kind of compositions preventing and treating Caulis et Folium Brassicae capitatae diamondback moth and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | disclosed |
| US-20120003188-A1 | Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived from Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2011150398-A1 | COMPOSITIONS AND METHODS OF USING LIVING AND NON-LIVING BIOACTIVE DEVICES WITH COMPONENTS DERIVED FROM SELF- RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | GARNET BIOTHERAPEUTICS, INC (US) | 2011-12-01 | — | — | WO | disclosed |
| EP-2171043-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | Garnet BioTherapeutics, Inc (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20090053183-A1 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | NEURONYX INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2008156728-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | NEURONYX, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-6566097-B2 | Polypeptide for use in the treatment of mammalian viral diseases | JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE (JP) | 2003-05-20 | — | — | US | disclosed |
| US-20020107366-A1 | Novel feline cytokine protein | TAKARA SHUZO CO., LTD. (JP) | 2002-08-08 | — | — | US | disclosed |
| US-5032506-A | Color control system | ENZYMATICS, INC. (US) | 1991-07-16 | — | — | US | disclosed |