SCHEMBL24070463

SCHEMBL24070463

C=CC(=O)N(C)CCCCCCCCCCCCS(=O)(=O)NC(=O)c1csc2c(-c3cc(Cl)ccc3C#CCn3c(C)nc4cnc(N(C)C5CCN(C6CC(F)(F)C6)CC5)c(C#N)c4c3=O)ccnc12

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EIF4EBP1 Q13541 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31668380 1.00 EIF4EBP1 (0.85) EIF4EBP1
SCHEMBL31668389 1.00 EIF4EBP1 (0.85) EIF4EBP1
SCHEMBL24069848 1.00 EIF4EBP1 (0.85) EIF4EBP1
SCHEMBL31668364 0.91 EIF4EBP1 (0.89) EIF4EBP1
SCHEMBL24070616 0.91 EIF4EBP1 (0.89) EIF4EBP1
Water SCHEMBL29885546 0.89 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29661934 0.89 EIF4EBP1 (1.00) EIF4EBP1
Water SCHEMBL27165018 0.89 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL22866515 0.89 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL22866517 0.86 EIF4EBP1 (1.00) EIF4EBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021240337-A1 COVALENT MODIFIERS OF EIF4E INHIBITING COMPOUNDS EFFECTOR THERAPEUTICS, INC. (US) 2021-12-02 — — WO disclosed
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