Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLQ | O75417 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074435 | 0.87 | STAT3 (0.51) | NPC1RAB9ASMN1; SMN2POLQALDH1A1 | |
| SCHEMBL24073697 | 0.86 | ADORA2A (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24073701 | 0.84 | POLQ (0.47) | NPC1RAB9ASMN1; SMN2POLQALDH1A1 | |
| SCHEMBL24072436 | 0.83 | POLQ (0.41) | NPC1RAB9ASMN1; SMN2POLQALDH1A1 | |
| SCHEMBL24073700 | 0.80 | MAPK14 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL25063115 | 0.80 | STAT3 (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24073694 | 0.80 | STAT3 (0.51) | NPC1RAB9ASMN1; SMN2POLQALDH1A1 | |
| SCHEMBL24072279 | 0.78 | MAPK14 (0.49) | NPC1RAB9AALDH1A1KMT2AKDM4E | |
| SCHEMBL24074431 | 0.75 | LCK (0.46) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24074613 | 0.75 | STAT3 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |