Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408038 | 1.00 | ABL1 (0.38) | ABL1CYP11B2FFAR4THRATHRB | |
| SCHEMBL2411071 | 0.86 | CYP11B1 (0.39) | ABL1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL2411065 | 0.86 | CYP11B1 (0.39) | ABL1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL2410664 | 0.86 | CYP19A1 (0.38) | ABL1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL2410659 | 0.86 | CYP19A1 (0.38) | ABL1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL2415380 | 0.85 | MKNK1 (0.40) | CYP11B2CYP11B1CYP17A1CYP1A2MKNK1 | |
| SCHEMBL2415378 | 0.85 | MKNK1 (0.40) | CYP11B2CYP11B1CYP17A1CYP1A2MKNK1 | |
| SCHEMBL2407924 | 0.85 | KDM4E (0.35) | CYP11B2CYP11B1CYP17A1CYP3A4CYP1A2 | |
| SCHEMBL2407918 | 0.85 | KDM4E (0.35) | CYP11B2CYP11B1CYP17A1CYP3A4CYP1A2 | |
| SCHEMBL314752 | 0.85 | CYP2A6 (0.39) | ABL1CYP11B2CYP11B1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013010-B2 | 5-thioxylopyranose compounds | LABORATOIRES FOURNIER S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | LABORATOIRES FOURNIER S.A (FR) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | TPMT, PNPO, CYP3A5 | ABL1 2708/4885CYP11B2 198/4885FFAR4 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.