Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.91 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407097 | 0.93 | HDAC1 (0.83) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2407996 | 0.93 | HDAC1 (0.83) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2408207 | 0.86 | HDAC1 (0.73) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2404840 | 0.85 | HDAC1 (0.76) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2405287 | 0.85 | HDAC1 (0.71) | HDAC1HDAC8HDAC6HDAC3ALDH1A1 | |
| SCHEMBL2406380 | 0.84 | HDAC1 (0.74) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2406452 | 0.84 | HDAC1 (0.74) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2408419 | 0.84 | HDAC1 (0.74) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL2407415 | 0.84 | SMN1; SMN2 (0.77) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL16297617 | 0.84 | HDAC1 (0.65) | HDAC1HDAC8HDAC6HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |