SCHEMBL240832

SCHEMBL240832

O=C(O)c1ccc(C#Cc2cc[c]cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.56
RARG P13631 5/20 0.56
PTPN11 Q06124 1/20 0.53
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
RARA P10276 2/20 0.46
CYP26A1 O43174 1/20 0.46
CYP3A4 P08684 1/20 0.46
CRABP2 P29373 1/20 0.46
SRD5A2 P31213 2/20 0.44
ACACB O00763 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
TYR P14679 1/20 0.43
DRD1 P21728 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29789030 0.87 RARB (0.69) RARBRARGPTPN11TSHRTP53
SCHEMBL69572 0.87 RARB (0.69) RARBRARGPTPN11TSHRTP53
Hydrochloric Acid SCHEMBL5666955 0.84 RARB (0.67) RARBRARGPTPN11TSHRTP53
SCHEMBL20764505 0.81 RARB (0.58) RARBRARGPTPN11TSHRTP53
SCHEMBL19433669 0.80 RARB (0.62) RARBRARGPTPN11TSHRTP53
SCHEMBL29023297 0.80 SRD5A2 (0.71) RARBRARGPTPN11TSHRTP53
SCHEMBL20026796 0.80 RARB (0.62) RARBRARGPTPN11TSHRTP53
SCHEMBL1535879 0.80 RARB (0.62) RARBRARGPTPN11TSHRTP53
SCHEMBL402518 0.80 RARB (0.62) RARBRARGPTPN11TSHRTP53
SCHEMBL5497692 0.80 RARB (0.49) RARBRARGPTPN11TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8231941-B2 Procedure for preparing redox-active polymers on surfaces THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-31 US claimed
US-20100330284-A1 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-30 US claimed
US-7452572-B1 Procedure for preparing redox-active polymers on surfaces THE NORTH CAROLINA STATE UNIVERSITY (US) 2008-11-18 US claimed
US-20080280047-A1 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-11-13 US claimed
US-7312100-B2 In situ patterning of electrolyte for molecular information storage devices THE NORTH CAROLINA STATE UNIVERSITY (US) 2007-12-25 US claimed
EP-1809473-A2 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-07-25 EP claimed
WO-2005086826-A2 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY (US) 2005-09-22 WO claimed
US-20050207208-A1 Situ patterning of electrolyte for molecular information storage devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2005-09-22 US claimed
US-6944047-B2 Variable-persistence molecular memory devices and methods of operation thereof NORTH CAROLINA STATE UNIVERSITY (US) 2005-09-13 US claimed
US-20040120180-A1 Variable-persistence molecular memory devices and methods of operation thereof NORTH CAROLINA STATE UNIVERSITY 2004-06-24 US claimed
US-6728129-B2 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-27 US claimed
US-20030169618-A1 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER 2003-09-11 US claimed
WO-2003071552-A1 MULTISTATE TRIPLE-DECKER DYADS IN THREE DISTINCT ARCHITECTURES FOR INFORMATION STORAGE APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-28 WO claimed
CN-117881432-A Porphyrin-hydrogen porphyrin compounds, compositions comprising the same, and methods of use thereof 北卡罗莱纳州立大学 2024-04-12 CN disclosed
EP-4319823-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF North Carolina State University (US) 2024-02-14 EP disclosed
WO-2022216927-A9 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2023-09-14 WO disclosed
US-20030169618-A1 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER 2003-09-11 US disclosed
WO-2003071552-A1 MULTISTATE TRIPLE-DECKER DYADS IN THREE DISTINCT ARCHITECTURES FOR INFORMATION STORAGE APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-28 WO disclosed
WO-2003052835-A1 METHOD AND SYSTEM FOR MOLECULAR CHARGE STORAGE FIELD EFFECT TRANSISTOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-06-26 WO disclosed
US-20030111670-A1 Method and system for molecular charge storage field effect transistor THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-06-19 US disclosed