Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300009 | 0.83 | STING1 (0.46) | STING1 | |
| SCHEMBL22300007 | 0.83 | STING1 (0.46) | STING1 | |
| SCHEMBL21856307 | 0.81 | STING1 (0.44) | STING1 | |
| SCHEMBL21856305 | 0.81 | STING1 (0.44) | STING1 | |
| SCHEMBL13341211 | 0.80 | STING1 (0.72) | STING1 | |
| SCHEMBL22300516 | 0.80 | STING1 (0.44) | STING1 | |
| SCHEMBL22300521 | 0.79 | STING1 (0.44) | STING1 | |
| SCHEMBL22300003 | 0.79 | STING1 (0.44) | STING1 | |
| SCHEMBL22299999 | 0.79 | STING1 (0.44) | STING1 | |
| SCHEMBL22299997 | 0.79 | STING1 (0.44) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535645-B2 | 6-mercaptopurine nucleoside analogues | LIAO XIBIN (US) | 2022-12-27 | — | — | US | disclosed |
| US-20210380628-A1 | 6-MERCAPTOPURINE NUCLEOSIDE ANALOGUES | LIAO XIBIN (US) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535645-B2 | 6-mercaptopurine nucleoside analogues | TPMT, TYMP, HPRT1 | STING1 2417/4885 |
| US-20210380628-A1 | 6-MERCAPTOPURINE NUCLEOSIDE ANALOGUES | TPMT, TYMP, HPRT1 | STING1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.