SCHEMBL24092197

SCHEMBL24092197

CCCCCCCCCCCCCCCC(=O)NCCOCCOCCC(=O)NCCOCCOCCC(=O)NCCCCC(NCC)C(=O)NC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.55
▸ NOD1 Q9Y239 1/20 0.41
▸ FAAH O00519 4/20 0.41
▸ TLR2 O60603 1/20 0.40
▸ FOLH1 Q04609 2/20 0.40
▸ CASP2 P42575 1/20 0.39
▸ SIRT2 Q8IXJ6 2/20 0.38
▸ NAAA Q02083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20936256 0.92 GLP1R (0.55) GLP1RNOD1FAAHCASP2SIRT2
SCHEMBL21572002 0.91 GLP1R (0.54) GLP1RNOD1FAAHTLR2CASP2
SCHEMBL19057814 0.87 GLP1R (0.51) GLP1RNOD1FAAHTLR2CASP2
SCHEMBL19057813 0.85 GLP1R (0.57) GLP1RNOD1FAAHTLR2FOLH1
SCHEMBL23552462 0.84 GLP1R (0.66) GLP1RNOD1FOLH1
SCHEMBL19057815 0.84 GLP1R (0.66) GLP1RNOD1FOLH1
SCHEMBL20936257 0.83 GLP1R (0.50) GLP1RFOLH1
SCHEMBL20936259 0.83 GLP1R (0.50) GLP1RFOLH1
SCHEMBL21571940 0.82 GLP1R (0.64) GLP1RNOD1FOLH1
SCHEMBL23552373 0.81 GLP1R (0.51) GLP1RNOD1FAAHFOLH1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11197914-B2 GLP-1R/GCGR dual target agonist polypeptide for treatment of fatty liver diseases, hyperlipemia and arteriosclerosis SHENZHEN TURIER BIOTECH CO. LTD. 2021-12-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11197914-B2 GLP-1R/GCGR dual target agonist polypeptide for treatment of fatty liver diseases, hyperlipemia and arteriosclerosis GLP1R, GCGR, GIPR GLP1R 1/4885NOD1 1131/4885FAAH 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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