SCHEMBL24092278

NC1C(O)[C@H](O)C(CO)O[C@@H]1OC1O[C@H](C[C@@H](O)[C@H]2O[C@@H](N3C=CC(O)NC3=O)[C@H](O)[C@@H]2O)C(O)C(O)[C@H]1N

nearest known ligand 0.48

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.37

▸	APEX1	P27695	1/20	0.37

▸	KMT2A	Q03164	1/20	0.37

▸	MAPT	P10636	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	BLM	P54132	1/20	0.33

▸	RECQL	P46063	1/20	0.33

▸	TDP1	Q9NUW8	1/20	0.33

▸	LMNA	P02545	1/20	0.32

▸	KDM4E	B2RXH2	1/20	0.32

▸	ALOX15	P16050	1/20	0.32

▸	HSD17B10	Q99714	1/20	0.31

▸	TSHR	P16473	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24092279	0.81	MEN1 (0.44)	MEN1APEX1KMT2AMAPTSMN1; SMN2
SCHEMBL22024082	0.78	SLC28A1 (0.60)	—
SCHEMBL22023770	0.78	SLC28A1 (0.60)	—
SCHEMBL22024084	0.78	SLC28A1 (0.60)	—
SCHEMBL22023772	0.78	SLC28A1 (0.60)	—
SCHEMBL20833069	0.76	CDA (0.47)	MAPTLMNA
SCHEMBL6674416	0.76	CDA (0.47)	MAPTLMNA
SCHEMBL20412282	0.74	SLC28A1 (0.54)	—
SCHEMBL20415958	0.71	SLC28A1 (0.49)	—
SCHEMBL20415979	0.70	P2RY14 (0.56)	MEN1APEX1KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3634974-B1	TUNICAMYCIN ANALOGUES	UNIV OXFORD INNOVATION LTD (GB)	2021-12-15	—	—	EP	disclosed