Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.90 |
| ▸ | S1PR3 | Q99500 | 14/20 | 0.90 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601422 | 0.95 | S1PR1 (1.00) | S1PR1S1PR3DRD3 | |
| SCHEMBL1601581 | 0.88 | S1PR1 (1.00) | S1PR1S1PR3DRD3 | |
| SCHEMBL1661439 | 0.80 | S1PR1 (0.81) | S1PR1S1PR3DRD3 | |
| SCHEMBL1661436 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3DRD3 | |
| SCHEMBL29565634 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3DRD3 | |
| SCHEMBL2412847 | 0.80 | S1PR1 (0.71) | S1PR1S1PR3DRD3 | |
| Hydrochloric Acid SCHEMBL1661541 | 0.80 | S1PR1 (0.80) | S1PR1S1PR3DRD3 | |
| Hydrochloric Acid SCHEMBL1661538 | 0.80 | S1PR1 (0.98) | S1PR1S1PR3DRD3 | |
| SCHEMBL3692568 | 0.78 | S1PR1 (0.82) | S1PR1S1PR3DRD3 | |
| SCHEMBL16143901 | 0.78 | S1PR1 (0.80) | S1PR1S1PR3DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364976-A1 | S1P receptor modulating compounds and use thereof | EPIX Pharmaceuticals, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |