Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 18/20 | 0.50 |
| ▸ | AOC2 | O75106 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095266 | 0.98 | AOC3 (0.50) | AOC3AOC2MAOA | |
| SCHEMBL24094929 | 0.92 | AOC3 (0.56) | AOC3 | |
| SCHEMBL24095107 | 0.92 | AOC3 (0.56) | AOC3 | |
| SCHEMBL21814766 | 0.91 | AOC3 (0.48) | AOC3AOC2MAOA | |
| SCHEMBL21814768 | 0.91 | AOC3 (0.48) | AOC3AOC2MAOA | |
| SCHEMBL24094936 | 0.90 | AOC3 (0.53) | AOC3AOC2MAOA | |
| SCHEMBL26264156 | 0.89 | AOC3 (0.39) | AOC3 | |
| SCHEMBL21815171 | 0.89 | AOC3 (0.46) | AOC3MAOA | |
| SCHEMBL21815174 | 0.89 | AOC3 (0.46) | AOC3MAOA | |
| SCHEMBL24095169 | 0.87 | AOC3 (0.48) | AOC3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787791-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230295140-A1 | INHIBITORS OF VAP-1 | ACUCELA INC. | 2023-09-21 | — | — | US | disclosed |
| US-20210387975-A1 | INHIBITORS OF VAP-1 | ACUCELA INC. | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787791-B2 | Inhibitors of VAP-1 | VAPB, VAPA, TOE1 | AOC3 290/4885AOC2 139/4885MAOA 1689/4885 |
| US-20230295140-A1 | INHIBITORS OF VAP-1 | VAPB, VAPA, TOE1 | AOC3 290/4885AOC2 139/4885MAOA 1689/4885 |
| US-20210387975-A1 | INHIBITORS OF VAP-1 | VAPB, VAPA, TOE1 | AOC3 290/4885AOC2 139/4885MAOA 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.