Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12234245 | 0.83 | ECE1 (0.36) | ALDH1A1HDAC2POLBGRIK1CTSC | |
| SCHEMBL22369843 | 0.83 | MAPT (0.41) | GRIK1MAPT | |
| SCHEMBL12234209 | 0.83 | MAPT (0.41) | GRIK1MAPT | |
| SCHEMBL26300607 | 0.83 | ECE1 (0.36) | ALDH1A1HDAC2POLBGRIK1CTSC | |
| SCHEMBL7412904 | 0.79 | SLC7A5 (0.50) | POLB | |
| SCHEMBL7412900 | 0.79 | SLC7A5 (0.50) | POLB | |
| SCHEMBL12234240 | 0.78 | SPHK1 (0.35) | ALDH1A1TDP1HDAC2POLBCTSC | |
| SCHEMBL13958827 | 0.78 | DPP7 (0.40) | ALDH1A1EPHX1HDAC2POLBCTSC | |
| SCHEMBL6494785 | 0.78 | DPP7 (0.41) | HDAC2POLBCTSC | |
| SCHEMBL24543395 | 0.78 | DPP7 (0.40) | ALDH1A1EPHX1HDAC2POLBCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |