Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875420 | 0.79 | CYP2C19 (0.37) | CYP2C19ALDH1A1HTTCYP11B2KDM4E | |
| SCHEMBL26918657 | 0.79 | CYP2C19 (0.37) | CYP2C19ALDH1A1HTTCYP11B2KDM4E | |
| SCHEMBL25717168 | 0.77 | CYP2C19 (1.00) | CYP2C19ALDH1A1HTTMAOAMAOB | |
| SCHEMBL29875581 | 0.76 | GRM5 (0.37) | CYP2C19CA1CA2CA4CA9 | |
| SCHEMBL21223411 | 0.76 | GRM5 (0.37) | CYP2C19CA1CA2CA4CA9 | |
| SCHEMBL4340447 | 0.76 | CYP2C19 (0.68) | CYP2C19ALDH1A1HTTMAOAMAOB | |
| SCHEMBL29922403 | 0.76 | CYP2C19 (0.68) | CYP2C19ALDH1A1HTTMAOAMAOB | |
| SCHEMBL23649534 | 0.76 | CYP2C19 (0.68) | CYP2C19ALDH1A1HTTCA1CA2 | |
| SCHEMBL29922033 | 0.76 | CYP2C19 (0.68) | CYP2C19ALDH1A1HTTCA1CA2 | |
| SCHEMBL29875663 | 0.74 | CYP2C19 (0.32) | CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192705-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| WO-2021249449-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192705-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | PTPN1, PTPN7, PTPN22 | CYP2C19 4213/4885ALDH1A1 4106/4885HTT 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.