Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411260 | 0.86 | PLCG1 (0.37) | HTR2CSLC6A4PDK2TACR1CACNA1G | |
| SCHEMBL15731438 | 0.86 | HTR2C (0.39) | HTR2CSLC6A4PDK2CACNA1GCACNA1B | |
| SCHEMBL5008198 | 0.84 | TACR1 (0.38) | TACR1FFAR4 | |
| SCHEMBL4430054 | 0.82 | PTGER2 (0.30) | HTR2CSLC6A4TACR1RIPK1 | |
| SCHEMBL30131039 | 0.81 | HTR2C (0.41) | HTR2CSLC6A4PDK2CACNA1GCACNA1B | |
| SCHEMBL1156849 | 0.81 | HTR2C (0.43) | HTR2CSLC6A4PDK2CACNA1GCACNA1B | |
| SCHEMBL1156833 | 0.81 | HTR2C (0.41) | HTR2CSLC6A4PDK2CACNA1GCACNA1B | |
| SCHEMBL1830977 | 0.81 | SSTR4 (0.38) | HTR2CSLC6A4PDK2TACR1CACNA1G | |
| SCHEMBL4566437 | 0.80 | FFAR4 (0.33) | TACR1GSK3BFFAR4 | |
| SCHEMBL1157177 | 0.79 | SLC6A4 (0.41) | HTR2CSLC6A4PDK2CACNA1GCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |