SCHEMBL24098809

SCHEMBL24098809

CCC1CC(CF)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.39
IRAK4 Q9NWZ3 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26651191 0.87 AR (0.40) ARIRAK4
SCHEMBL2793908 0.82 PRKCD (0.37) ARIRAK4
SCHEMBL7507854 0.82 PRKCD (0.37) ARIRAK4
SCHEMBL17137283 0.82 PRKCD (0.37) ARIRAK4
SCHEMBL12616420 0.74
SCHEMBL26045076 0.74
SCHEMBL26045078 0.74
SCHEMBL30913158 0.74
SCHEMBL24250230 0.73 CREBBP (0.32)
SCHEMBL10957929 0.71 AR (0.34) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021252849-A1 INHIBITORS OF APOL1 AND USE OF THE SAME VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-12-16 WO disclosed