Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 10/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098693 | 0.86 | RXFP1 (0.69) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24099252 | 0.84 | RXFP1 (0.60) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL30380917 | 0.84 | RXFP1 (0.60) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24099052 | 0.83 | TP53 (0.68) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL30380730 | 0.83 | TP53 (0.68) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24099006 | 0.82 | RXFP1 (0.76) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24121089 | 0.82 | RXFP1 (0.62) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24121070 | 0.81 | RXFP1 (0.62) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24120852 | 0.81 | TP53 (0.74) | RXFP1LMNATP53THRBMAPT | |
| SCHEMBL24121079 | 0.81 | TP53 (0.61) | RXFP1LMNATP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252775-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. (US) | 2021-12-16 | — | — | WO | disclosed |