Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15248190 | 0.97 | KDM4E (0.50) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL23329677 | 0.97 | KDM4E (0.50) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL15747036 | 0.97 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL20408490 | 0.97 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL19001868 | 0.95 | KDM4E (0.46) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL26712483 | 0.95 | KDM4E (0.55) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL12196587 | 0.95 | KDM4E (0.55) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL10118674 | 0.95 | KDM4E (0.58) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL9917245 | 0.95 | KDM4E (0.58) | KDM4EATML3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL9917211 | 0.95 | KDM4E (0.58) | KDM4EATML3MBTL1ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917906-B2 | Compounds that can be used in an organic electronic device | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917906-B2 | Compounds that can be used in an organic electronic device | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20210391538-A1 | COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2021-12-16 | — | — | US | disclosed |