Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.72 |
| ▸ | PGR | P06401 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 3/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25863725 | 0.92 | AR (0.72) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL25863727 | 0.92 | AR (0.72) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL12355440 | 0.92 | AR (0.72) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL24102447 | 0.92 | AR (0.72) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL13125416 | 0.91 | AR (0.70) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL3452466 | 0.91 | AR (0.70) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL5030883 | 0.91 | AR (0.70) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL25863522 | 0.90 | AR (0.78) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL25863524 | 0.90 | AR (0.78) | ARPGRMAPTLMNANR3C2 | |
| SCHEMBL25863641 | 0.90 | AR (0.84) | ARPGRMAPTLMNANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252761-A2 | MONOMERIC AND OLIGOMERIC COMPOUND EMBODIMENTS AS CONTRACEPTIVES AND THERAPIES AND METHODS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-12-16 | — | — | WO | disclosed |