Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868255 | 0.94 | AR (0.66) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102423 | 0.91 | AR (0.62) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24103137 | 0.91 | AR (0.62) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102628 | 0.90 | AR (0.62) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL25863275 | 0.89 | AR (0.79) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102638 | 0.89 | AR (0.59) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL25863274 | 0.89 | AR (0.79) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102412 | 0.88 | AR (0.67) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102832 | 0.88 | AR (0.65) | ARMAPTLMNAPGRCYP3A4 | |
| SCHEMBL24102820 | 0.88 | AR (0.65) | ARMAPTLMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252761-A2 | MONOMERIC AND OLIGOMERIC COMPOUND EMBODIMENTS AS CONTRACEPTIVES AND THERAPIES AND METHODS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-12-16 | — | — | WO | disclosed |