Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.63 |
| ▸ | CDK2 | P24941 | 20/20 | 0.63 |
| ▸ | CCND1 | P24385 | 16/20 | 0.63 |
| ▸ | CDK6 | Q00534 | 16/20 | 0.63 |
| ▸ | CDK4 | P11802 | 7/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.63 |
| ▸ | CDK9 | P50750 | 6/20 | 0.63 |
| ▸ | CCND3 | P30281 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669655 | 0.84 | CCNE1 (0.68) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24668707 | 0.83 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24668728 | 0.82 | CCNE1 (0.66) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24668696 | 0.81 | CCNE1 (0.65) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24669656 | 0.80 | CCNE1 (0.59) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26099327 | 0.80 | CCNE1 (0.79) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26099333 | 0.80 | CCNE1 (0.79) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24669537 | 0.79 | CCNE1 (0.58) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24670431 | 0.79 | CCNE1 (0.75) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24669062 | 0.78 | CCNE1 (0.59) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249258-A1 | DEUTERATED PYRIDOPYRIMIDINONES AND THEIR USE AS HIGHLY SELECTIVE CYCLIN-DEPENDENT KINASE 2 INHIBITORS | ZENTAUR THERAPEUTICS INTERNATIONAL LIMITED (CN) | 2021-12-16 | — | — | WO | disclosed |