Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 12/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112462 | 0.96 | TTK (0.50) | TTKAXLPTK2 | |
| SCHEMBL22124077 | 0.93 | TTK (0.45) | TTKAXLPTK2PTK6SYK | |
| SCHEMBL24940111 | 0.93 | TTK (0.45) | TTKAXLPTK2PTK6SYK | |
| SCHEMBL24940026 | 0.93 | TTK (0.45) | TTKAXLPTK2PTK6SYK | |
| SCHEMBL30385447 | 0.91 | TTK (0.44) | TTKAXLPTK2CCNA2CDK2 | |
| SCHEMBL22124088 | 0.90 | TTK (0.47) | TTKAXLPTK2PTK6 | |
| SCHEMBL25450828 | 0.90 | TTK (0.43) | TTKAXLPTK2PTK6SYK | |
| Hydrochloric Acid SCHEMBL25169297 | 0.90 | TTK (0.43) | TTKAXLPTK2PTK6SYK | |
| Hydrochloric Acid SCHEMBL25169296 | 0.90 | TTK (0.43) | TTKAXLPTK2PTK6SYK | |
| SCHEMBL24940127 | 0.89 | TTK (0.47) | TTKAXLPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |