Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.44 |
| ▸ | AXL | P30530 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139189 | 0.94 | TTK (0.43) | TTKAXL | |
| SCHEMBL22123713 | 0.94 | TTK (0.43) | TTKAXL | |
| SCHEMBL22139188 | 0.94 | TTK (0.43) | TTKAXL | |
| SCHEMBL24940098 | 0.94 | TTK (0.43) | TTKAXL | |
| SCHEMBL25445368 | 0.92 | TTK (0.42) | TTKAXL | |
| SCHEMBL22139190 | 0.92 | TTK (0.45) | TTKAXL | |
| SCHEMBL30171550 | 0.92 | TTK (0.45) | TTKAXL | |
| SCHEMBL24112462 | 0.91 | TTK (0.50) | TTKAXL | |
| SCHEMBL25450847 | 0.91 | TTK (0.41) | TTKAXL | |
| SCHEMBL30385495 | 0.91 | TTK (0.43) | TTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |