Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | STK4 | Q13043 | 2/20 | 0.31 |
| ▸ | STK3 | Q13188 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112346 | 0.90 | PTK6 (0.39) | PTK6LCKAURKBP2RX3EGFR | |
| SCHEMBL24112380 | 0.85 | PTK6 (0.35) | PTK6EGFRIGF1R | |
| SCHEMBL30171867 | 0.85 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL22123725 | 0.85 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL30386185 | 0.84 | PTK6 (0.40) | PTK6LCKAURKB | |
| SCHEMBL25176442 | 0.84 | PTK6 (0.40) | PTK6LCKAURKBEGFR | |
| SCHEMBL22123122 | 0.84 | PTK6 (0.44) | PTK6LCKAURKB | |
| SCHEMBL22124776 | 0.84 | PTK6 (0.37) | PTK6LCKAURKBEGFRSTK4 | |
| SCHEMBL30171624 | 0.84 | PTK6 (0.44) | PTK6LCKAURKB | |
| SCHEMBL30402469 | 0.84 | PTK6 (0.37) | PTK6LCKAURKBEGFRSTK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |