Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 10/20 | 0.40 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170323 | 0.93 | MAPKAPK5 (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL22124730 | 0.93 | TTK (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL25450721 | 0.92 | MAPKAPK5 (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| Hydrochloric Acid SCHEMBL25176395 | 0.92 | MAPKAPK5 (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| Hydrochloric Acid SCHEMBL30386094 | 0.92 | MAPKAPK5 (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL25444498 | 0.91 | TTK (0.40) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL22124330 | 0.91 | MAPKAPK5 (0.42) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL22123692 | 0.91 | MAPKAPK5 (0.43) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL22154245 | 0.90 | MAPKAPK5 (0.42) | MAPKAPK5TTKSYKPTK6AURKB | |
| SCHEMBL25446266 | 0.90 | TTK (0.40) | MAPKAPK5TTKSYKPTK6AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |