Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22160896 | 0.98 | PTK6 (0.36) | SYKPTK6TTKAXLHTT | |
| SCHEMBL24917127 | 0.95 | TTK (0.35) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL24870783 | 0.95 | TTK (0.37) | SYKPTK6TTKHPGDAXL | |
| SCHEMBL25452873 | 0.94 | PTK6 (0.35) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL22160344 | 0.94 | SYK (0.37) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL25014260 | 0.94 | PTK6 (0.35) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL22123449 | 0.94 | SYK (0.36) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL22123676 | 0.94 | SYK (0.36) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL22123913 | 0.94 | SYK (0.36) | SYKPTK6TTKAXLMAPKAPK5 | |
| SCHEMBL22123726 | 0.94 | SYK (0.36) | SYKPTK6TTKAXLMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |