Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411248 | 1.00 | SOS1 (0.63) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL5440780 | 0.88 | SOS1 (0.71) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL5440784 | 0.88 | SOS1 (0.71) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL14935499 | 0.84 | MAPT (0.69) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL11049170 | 0.84 | MAPT (0.69) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL9978289 | 0.84 | MAPT (0.69) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL3846864 | 0.83 | SOS1 (0.65) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL29414981 | 0.83 | SOS1 (0.65) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL3846862 | 0.83 | SOS1 (0.65) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL566396 | 0.83 | SOS1 (0.65) | SOS1MAPTMAOBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237836-A1 | Method for Producing Alkylnitrobenzenes and Alkylanilines, Unbranched in the 1'-Position, from Nitrotoluenes | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110237836-A1 | Method for Producing Alkylnitrobenzenes and Alkylanilines, Unbranched in the 1'-Position, from Nitrotoluenes | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| CN-101489977-A | Nitrobenzene derivatives and process for preparing said 1' alkylnitrobenzenes and alkylanilines | BAYER CROPSCIENCE AG (DE) | 2009-07-22 | — | — | CN | disclosed |
| EP-2046720-A2 | NITROBENZOL DERIVATIVES AND METHOD FOR PRODUCING SAID 1' ALKYLNITROBENZENES AND ALKYLANILINES | Bayer CropScience Aktiengesellschaft (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008006574-A2 | NITROBENZOL DERIVATIVES AND METHOD FOR PRODUCING SAID 1' ALKYLNITROBENZENES AND ALKYLANILINES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008006574-A2 | NITROBENZOL DERIVATIVES AND METHOD FOR PRODUCING SAID 1' ALKYLNITROBENZENES AND ALKYLANILINES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237836-A1 | Method for Producing Alkylnitrobenzenes and Alkylanilines, Unbranched in the 1'-Position, from Nitrotoluenes | CYP1B1, CYP1A1, CYP1A2 | SOS1 3514/4885MAPT 3912/4885MAOB 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.