Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 11/20 | 0.43 |
| ▸ | AXL | P30530 | 4/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112411 | 1.00 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| SCHEMBL24112472 | 0.97 | TTK (0.42) | TTKAXLSYK | |
| Hydrochloric Acid SCHEMBL25170369 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| SCHEMBL24112582 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| Hydrochloric Acid SCHEMBL25170371 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| SCHEMBL25450812 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| Hydrochloric Acid SCHEMBL25173476 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| SCHEMBL24112410 | 0.92 | TTK (0.43) | TTKAXLPTK6SYKPTK2 | |
| SCHEMBL30385494 | 0.89 | USP30 (0.45) | TTKPTK2 | |
| SCHEMBL30385782 | 0.89 | USP30 (0.45) | TTKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |