Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 9/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 5/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112501 | 0.95 | PTK2 (0.34) | TTKPTK6AXLPTK2 | |
| Trifluoroacetic Acid SCHEMBL30386143 | 0.94 | TTK (0.34) | TTKPTK6 | |
| SCHEMBL25451174 | 0.94 | TTK (0.39) | TTKPTK6AXLPTK2 | |
| SCHEMBL24112321 | 0.92 | TTK (0.33) | TTKPTK6PTK2 | |
| Trifluoroacetic Acid SCHEMBL30385559 | 0.90 | TTK (0.33) | TTKPTK2 | |
| SCHEMBL24112510 | 0.90 | PTK2 (0.37) | TTKPTK6AXLPTK2 | |
| Trifluoroacetic Acid SCHEMBL30386136 | 0.90 | TTK (0.39) | TTKPTK6AXLPTK2 | |
| Trifluoroacetic Acid SCHEMBL30384678 | 0.89 | TTK (0.33) | TTKPTK6PTK2 | |
| SCHEMBL24112435 | 0.89 | TTK (0.31) | TTKPTK6PTK2 | |
| SCHEMBL24112422 | 0.88 | PTK6 (0.32) | TTKPTK6PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |