Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 13/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.33 |
| ▸ | LCK | P06239 | 6/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | JAK1 | P23458 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112613 | 0.96 | PTK6 (0.39) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL32675710 | 0.96 | PTK6 (0.39) | PTK6AURKBLCK | |
| SCHEMBL24112644 | 0.96 | PTK6 (0.39) | PTK6AURKBLCK | |
| SCHEMBL25450939 | 0.93 | PTK6 (0.38) | PTK6AURKBLCKJAK2JAK1 | |
| Trifluoroacetic Acid SCHEMBL25167712 | 0.93 | PTK6 (0.36) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL24112643 | 0.93 | PTK6 (0.41) | PTK6AURKBLCK | |
| Trifluoroacetic Acid SCHEMBL30385230 | 0.93 | PTK6 (0.36) | PTK6AURKBLCK | |
| SCHEMBL24112409 | 0.92 | PTK6 (0.39) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL32675702 | 0.92 | PTK6 (0.39) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL24112431 | 0.91 | PTK6 (0.38) | PTK6AURKBLCKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |