Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | DDO | Q99489 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208058 | 0.87 | DAO (0.58) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL24113304 | 0.85 | DAO (0.56) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL24019648 | 0.84 | DAO (0.55) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL23836114 | 0.81 | GRIN2D (0.56) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL22620711 | 0.81 | KDM4E (0.56) | DAODDOMAPTMEN1KMT2A | |
| SCHEMBL24113038 | 0.80 | DAO (0.54) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL24019680 | 0.79 | MEN1 (0.53) | DAODDOHTR6GRIN2DGRIN1 | |
| SCHEMBL24112430 | 0.78 | HRH4 (0.59) | DAOGRIN1HRH4FLT3PDGFRB | |
| SCHEMBL16234660 | 0.78 | HRH4 (0.59) | DAODDOGRIN2DGRIN1GRIN2A | |
| SCHEMBL38664122 | 0.77 | HRH4 (0.57) | DAODDOGRIN2DGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |