Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20684327 | 0.92 | SCN8A (0.42) | SCN8AFFAR4KMT2AMEN1KDM4E | |
| SCHEMBL24113746 | 0.87 | SCN8A (0.33) | SCN8AFFAR4KMT2AMEN1KDM4E | |
| SCHEMBL24113750 | 0.85 | MRGPRX4 (0.40) | SCN8AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL16333319 | 0.84 | SCN8A (0.32) | SCN8AMAPTL3MBTL1GRIN2DGRIN3B | |
| SCHEMBL25436252 | 0.82 | SCN8A (0.40) | SCN8AFFAR4KMT2AMEN1KDM4E | |
| SCHEMBL17689130 | 0.82 | GRIN2D (0.38) | KDM4EALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL22593864 | 0.79 | SCN8A (0.36) | SCN8AFFAR4KMT2AMEN1KDM4E | |
| SCHEMBL21777805 | 0.78 | MAPT (0.49) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL814826 | 0.78 | SCN8A (0.35) | SCN8AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29864603 | 0.78 | SCN8A (0.35) | SCN8AKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925989-A1 | MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS | Dow Global Technologies LLC (US) | 2021-12-22 | — | — | EP | disclosed |