Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22309058 | 0.94 | TUBB1 (0.40) | TUBB1AKT1 | |
| SCHEMBL22309078 | 0.86 | TUBB1 (0.43) | TUBB1 | |
| SCHEMBL20732428 | 0.83 | TUBB1 (0.54) | TUBB1AKT1 | |
| SCHEMBL24410027 | 0.83 | TUBB1 (0.54) | TUBB1AKT1 | |
| SCHEMBL22307928 | 0.81 | AKT1 (0.33) | TUBB1AKT1 | |
| SCHEMBL22309199 | 0.80 | TUBB1 (0.37) | TUBB1AKT1 | |
| SCHEMBL22309065 | 0.78 | AKT1 (0.34) | AKT1 | |
| SCHEMBL22111348 | 0.78 | TUBB1 (0.49) | TUBB1 | |
| SCHEMBL22309211 | 0.77 | AKT1 (0.34) | TUBB1AKT1 | |
| SCHEMBL22309273 | 0.77 | AKT1 (0.34) | TUBB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925668-A1 | HEMIASTERLIN DERIVATIVE HAVING CYSTEINE RESIDUE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-12-22 | — | — | EP | disclosed |