Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370547 | 1.00 | TSHR (0.52) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL29373532 | 1.00 | TSHR (0.52) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL7247288 | 0.98 | TSHR (0.50) | TSHRMAPTALOX15HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL28292055 | 0.98 | TSHR (0.50) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL4504383 | 0.98 | TSHR (0.50) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL19996347 | 0.98 | TSHR (0.50) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL2425535 | 0.98 | TSHR (0.50) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL28370551 | 0.96 | TSHR (0.54) | TSHRMAPTALOX15HSD17B10NPC1 | |
| SCHEMBL28345077 | 0.96 | TSHR (0.48) | TSHRMAPTALOX15HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL19742945 | 0.96 | TSHR (0.48) | TSHRMAPTALOX15HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2493 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383913-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2024-11-21 | — | — | US | claimed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | claimed |
| US-20240052256-A1 | BENZAZEPINE COMPOUNDS AS ANTIOXIDANTS FOR LUBRICANT COMPOSITIONS | THE LUBRIZOL CORPORATION | 2024-02-15 | — | — | US | claimed |
| US-20230386615-A1 | BINDING SITE IN TYPE 1 RYANODINE RECEPTOR | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-11-30 | — | — | US | claimed |
| US-20230368862-A1 | BINDING SITE IN TYPE 2 RYANODINE RECEPTOR | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-11-16 | — | — | US | claimed |
| EP-4267707-A1 | BENZAZEPINE COMPOUNDS AS ANTIOXIDANTS FOR LUBRICANT COMPOSITIONS | The Lubrizol Corporation (US) | 2023-11-01 | — | — | EP | claimed |
| US-20230339882-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-10-26 | — | — | US | claimed |
| CN-116685663-A | Benzazepine compounds as antioxidants for lubricating compositions | 路博润公司 | 2023-09-01 | — | — | CN | claimed |
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | claimed |
| CN-116496216-A | Preparation method of tetrahydrobenzazepine condensed ring derivative | 华中科技大学 | 2023-07-28 | — | — | CN | claimed |
| US-6034117-A | Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method | PHARMAPNEA AB (SE) | 2000-03-07 | — | — | US | claimed |
| EP-0923570-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | Klinge Pharma GmbH (DE) | 1999-06-23 | — | — | EP | claimed |
| US-5863924-A | Aryl pyrimidine derivatives | SYNTEX (U.S.A.) INC. (US) | 1999-01-26 | — | — | US | claimed |
| WO-1997048696-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | claimed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | claimed |
| EP-0566069-A1 | Tachykinin receptor antagonists, isoquinolones and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| WO-1992019572-A2 | I-AZA-2-PHENYLHYDRORAZINO-HETEROCYCLES, PROCESS FOR PRODUCING THEM AND PHARMACEUTICALS CONTAINING THEM | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1992-11-12 | — | — | WO | claimed |
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | claimed |
| EP-0119896-A1 | 5-Amino-1,2-dithiol-3-one derivatives, their preparation and medicinal compositions containing them | RHONE-POULENC SANTE (FR) | 1984-09-26 | — | — | EP | claimed |