Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124302 | 0.89 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL24124286 | 0.88 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL24124280 | 0.83 | ANO1 (0.49) | KMT2ASMN1; SMN2MEN1KDM4EKCNK3 | |
| SCHEMBL30522641 | 0.82 | MAPT (0.58) | KMT2ASMN1; SMN2MEN1MAPTALDH1A1 | |
| SCHEMBL24124922 | 0.82 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL25323225 | 0.82 | MAPT (0.58) | KMT2ASMN1; SMN2MEN1MAPTALDH1A1 | |
| SCHEMBL24124926 | 0.79 | KCNK3 (0.46) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL24124918 | 0.77 | KMT2A (0.46) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL24124919 | 0.75 | KMT2A (0.59) | KMT2ASMN1; SMN2MEN1KDM4EPOLB | |
| SCHEMBL30522642 | 0.75 | KMT2A (0.59) | KMT2ASMN1; SMN2MEN1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |