Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30270587 | 0.82 | CYP1A2 (0.58) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL25921866 | 0.82 | CYP1A2 (0.58) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124186 | 0.81 | MAPT (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124898 | 0.81 | MAPT (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124676 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124884 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL25920636 | 0.79 | MAPT (0.60) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124188 | 0.79 | MAPT (0.62) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24124800 | 0.76 | MAPT (0.62) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL25921176 | 0.76 | CNR2 (0.52) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |