Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 8/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 7/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595972 | 1.00 | PDCD1 (0.51) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL24127450 | 0.94 | PDCD1 (0.45) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL30595960 | 0.94 | PDCD1 (0.45) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL30596010 | 0.89 | MAP3K5 (0.47) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL24127440 | 0.89 | MAP3K5 (0.47) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL24127333 | 0.89 | PRMT5 (0.42) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL30595962 | 0.89 | PRMT5 (0.42) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL24127327 | 0.88 | MAP3K5 (0.40) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL30595971 | 0.88 | MAP3K5 (0.40) | PDCD1CD274PRMT5WDR77MAP3K5 | |
| SCHEMBL24127451 | 0.87 | MAP3K5 (0.43) | PDCD1CD274PRMT5WDR77MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| EP-4174066-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-05-03 | — | — | EP | disclosed |
| EP-4174066-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-05-03 | — | — | EP | disclosed |
| WO-2021254005-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | PDCD1 2/4885CD274 1/4885PRMT5 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.