⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419921 | 0.99 | — | — | |
| SCHEMBL2414779 | 0.94 | SCD (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL2412790 | 0.91 | PPARG (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL2419917 | 0.90 | PPARG (0.32) | — | |
| SCHEMBL12273687 | 0.89 | PPARA (0.32) | — | |
| SCHEMBL2411564 | 0.89 | — | — | |
| SCHEMBL12277220 | 0.88 | PPARA (0.32) | — | |
| SCHEMBL2415135 | 0.87 | — | — | |
| SCHEMBL2410256 | 0.86 | HPGD (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL2414777 | 0.85 | HRH4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | MITSUBISHI PHAMA CORPORATION (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |