⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908243 | 0.87 | — | — | |
| SCHEMBL190387 | 0.81 | — | — | |
| SCHEMBL20661653 | 0.81 | — | — | |
| SCHEMBL7142061 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL179841 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL3416020 | 0.81 | — | — | |
| SCHEMBL476458 | 0.78 | DPP7 (0.37) | — | |
| SCHEMBL633836 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9031347 | 0.78 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL24971854 | 0.78 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987244-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2015-03-24 | — | — | US | claimed |
| US-20140113969-A1 | Preventing And/Or Treating Cardiovascular Disease And/Or Associated Heart Failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2014-04-24 | — | — | US | claimed |
| US-6951890-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PROTEMIX CORPORATION LIMITED (NZ) | 2005-10-04 | — | — | US | claimed |
| US-20030203973-A1 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2003-10-30 | — | — | US | claimed |
| US-20230364031-A1 | TREATMENT OF BRAIN COPPER DISORDERS | PHILERA NEW ZEALAND LTD. (NZ) | 2023-11-16 | — | — | US | disclosed |
| US-8987244-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2015-03-24 | — | — | US | disclosed |
| US-20140113969-A1 | Preventing And/Or Treating Cardiovascular Disease And/Or Associated Heart Failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2014-04-24 | — | — | US | disclosed |
| US-8563538-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2013-10-22 | — | — | US | disclosed |
| EP-2500018-A1 | Preventing and/or Treating Cardiovascular Disease and/or Associated Heart Failure | PhilERA New Zealand Limited (NZ) | 2012-09-19 | — | — | EP | disclosed |
| EP-1487431-B1 | PREVENTING AND/OR TREATING CARDIOVASCULAR DISEASE AND/OR ASSOCIATED HEART FAILURE | PHILERA NEW ZEALAND LTD (NZ) | 2012-05-02 | — | — | EP | disclosed |
| US-8034799-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2011-10-11 | — | — | US | disclosed |
| US-20110212188-A1 | PREVENTING AND/OR TREATING CARDIOVASCULAR DISEASE AND/OR ASSOCIATED HEART FAILURE | PHILERA NEW ZEALAND LIMITED (NZ) | 2011-09-01 | — | — | US | disclosed |
| US-20070148689-A1 | Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases | LEISHMAN KATHRYN | 2007-06-28 | — | — | US | disclosed |
| US-20060009534-A1 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2006-01-12 | — | — | US | disclosed |
| US-6951890-B2 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PROTEMIX CORPORATION LIMITED (NZ) | 2005-10-04 | — | — | US | disclosed |
| US-20030203973-A1 | Preventing and/or treating cardiovascular disease and/or associated heart failure | PHILERA NEW ZEALAND LIMITED (NZ) | 2003-10-30 | — | — | US | disclosed |