Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.79 |
| ▸ | CDK2 | P24941 | 20/20 | 0.79 |
| ▸ | CCND1 | P24385 | 17/20 | 0.79 |
| ▸ | CDK6 | Q00534 | 17/20 | 0.79 |
| ▸ | CDK4 | P11802 | 4/20 | 0.73 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.73 |
| ▸ | CDK9 | P50750 | 3/20 | 0.73 |
| ▸ | CCND3 | P30281 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24132124 | 0.92 | CCNE1 (0.84) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19863598 | 0.89 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29641049 | 0.88 | CCNE1 (0.81) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24132126 | 0.86 | CCNE1 (0.81) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19863597 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19857324 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL24131207 | 0.85 | CCNE1 (0.68) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19857311 | 0.85 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL31153371 | 0.85 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29640992 | 0.85 | CCNE1 (0.84) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254384-A1 | NOVEL PYRIDO[2,3-D]PYRIMIDINE-7(8H)-ONE DERIVATIVE | 微境生物医药科技(上海)有限公司 | 2021-12-23 | — | — | WO | disclosed |