Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 18/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24135363 | 0.87 | RET (0.38) | RETKCNJ1 | |
| SCHEMBL21850904 | 0.87 | KCNJ1 (0.46) | RETKCNJ1 | |
| SCHEMBL21850793 | 0.82 | KCNJ1 (0.45) | RETKCNJ1 | |
| SCHEMBL21851170 | 0.80 | KCNJ1 (0.45) | RETKCNJ1 | |
| SCHEMBL21850937 | 0.76 | CXCR4 (0.40) | RETKCNJ1 | |
| SCHEMBL24135318 | 0.76 | KCNJ1 (0.43) | RETKCNJ1 | |
| SCHEMBL24135381 | 0.74 | RET (0.35) | RETKCNJ1 | |
| SCHEMBL21850946 | 0.72 | KCNJ1 (0.56) | RETKCNJ1 | |
| SCHEMBL21851187 | 0.72 | KCNJ1 (0.42) | KCNJ1 | |
| SCHEMBL21850952 | 0.70 | KCNJ1 (0.39) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929194-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | Bristol-Myers Squibb Company (US) | 2021-12-29 | — | — | EP | disclosed |