Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21018534 | 1.00 | GRIN1 (0.65) | GRIN1GRIN2B | |
| SCHEMBL17643289 | 0.88 | GRIN1 (0.67) | GRIN1GRIN2B | |
| SCHEMBL30648113 | 0.87 | GRIN1 (0.55) | GRIN1GRIN2B | |
| SCHEMBL20090862 | 0.87 | GRIN1 (0.65) | GRIN1GRIN2B | |
| SCHEMBL17643129 | 0.85 | GRIN1 (0.69) | GRIN1GRIN2B | |
| SCHEMBL22701586 | 0.84 | GRIN1 (0.62) | GRIN1GRIN2B | |
| SCHEMBL20841769 | 0.84 | GRIN1 (0.69) | GRIN1GRIN2B | |
| SCHEMBL22701542 | 0.84 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL20091017 | 0.84 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL21018705 | 0.84 | GRIN1 (0.47) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-B1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2021-12-29 | — | — | EP | disclosed |