Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701601 | 0.86 | GRIN1 (0.51) | GRIN1GRIN2BRAB9ATSHRHSD17B10 | |
| SCHEMBL20090989 | 0.86 | GRIN1 (0.51) | GRIN1GRIN2BRAB9ATSHRHSD17B10 | |
| SCHEMBL20086399 | 0.82 | GRIN1 (0.84) | GRIN1GRIN2B | |
| SCHEMBL17633325 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL28383540 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17643109 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL24136434 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17643440 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17633322 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL24136486 | 0.80 | GRIN2B (0.60) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-B1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2021-12-29 | — | — | EP | disclosed |