⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254237 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL21816614 | 0.76 | — | — | |
| SCHEMBL24773510 | 0.75 | — | — | |
| SCHEMBL8717205 | 0.74 | PRMT1 (0.50) | — | |
| SCHEMBL18950460 | 0.74 | PRMT1 (0.50) | — | |
| SCHEMBL29074467 | 0.74 | PRMT1 (0.50) | — | |
| SCHEMBL4270520 | 0.74 | PRMT1 (0.50) | — | |
| SCHEMBL24979647 | 0.72 | — | — | |
| SCHEMBL5579827 | 0.72 | PRMT1 (0.48) | — | |
| SCHEMBL10052764 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928779-A1 | PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. | Chugai Seiyaku Kabushiki Kaisha (JP) | 2021-12-29 | — | — | EP | disclosed |