SCHEMBL24138255

SCHEMBL24138255

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nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.69
ABCB1 P08183 1/20 0.40
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1320767 0.85 TDP1 (0.66) TDP1ABCB1POLBMAPK1
SCHEMBL9218716 0.84 TDP1 (0.81) TDP1ABCB1POLBMAPK1
SCHEMBL7150717 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL826717 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL7152317 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL270042 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL2175855 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL7149374 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL13168216 0.84 TDP1 (0.96) TDP1ABCB1POLBMAPK1
SCHEMBL17635918 0.83 TDP1 (0.79) TDP1ABCB1POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021263039-A1 AMPK ACTIVATORS KALLYOPE, INC. (US) 2021-12-30 WO disclosed